Research

The faculty associated with the Division of Infectious Diseases at UCSF have diverse and complementary research interests in clinical, translational, and basic research. ID faculty have a rich tradition of well-funded grant support as part of the top two NIH-funded departments of medicine in the country. The ID faculty are leading critical studies which include: microbial pathogenesis, the nature of allergic and inflammatory immunity, the development of microarray and deep sequencing technologies for viral pathogen discovery and clinical diagnostics, and HPV immunology, epidemiology, and clinical trials on HPV disease treatment and prevention. Faculty in our Training in Malarial Research in Uganda Program study optimal treatment and prevention strategies for malaria control as well as the immunology of malaria and mechanisms of antimalarial drug resistance. Our AIDS faculty are critically evaluating new treatments for HIV and associated complications such as TB and hepatitis, and are looking at novel approaches to HIV care delivery in the US and overseas. As a testament to the rich and collaborative environment here, infectious diseases research at UCSF often transcends traditional disciplines and occurs in a variety of affiliated sites. These range from Mission Bay, Parnassus, the VA Hospital, and San Francisco General Hospital campuses to the San Francisco Department of Public Health, the Center for AIDS Prevention Studies, and the University of California at Berkeley, as well as other countries as part of our global health research program.

Research for fellows

Infectious diseases fellows typically devote most of their time to research starting in the second year of fellowship. A variety of NIH-supported training grants support ID fellows during this period, such as the UCSF Biology of Infectious Disease Training grant, Traineeship in AIDS Prevention Studies. Depending on the specific training grant, interested fellows may also undertake coursework at the UC Berkeley School of Public Health (for a Masters of Public Health), as well as the UCSF Department of Epidemiology and Biostatistics and the Clinical and Translational Sciences Institute Training Program (towards a Certificate Program or a Masters in Clinical Research). In addition to several University-wide and Division-sponsored research colloquia that occur during the year, the Division of Infectious Diseases sponsors an annual Biology of Infectious Diseases research retreat, where fellows and junior faculty present their research works-in-progress to a wide array of faculty and trainees.

We recommend that applicants identify potential areas of research prior to the interview. During the interview process, we will attempt to make connections between applicants and potential mentors and research areas of interest. In addition, we hold a variety of sessions prior to and during the first year of fellowship to help fellows choose the appropriate mentorship team and projects. The research mentor then works closely with the mentor assigned from the ID training program to ensure fellows’ success and happiness.

A partial list of potential research areas and mentors follows.

Clinical/Translational Research

Chagas disease Clinical pharmacy Emerging diseases Hepatitis HIV epidemiology HIV global health HIV transplant HIV treatment HIV prevention Human papillomavirus Infection control Malaria Sexually transmitted infections S. aureus Transplant Infectious Disease Tuberculosis

Basic Research

Bartonella Cryptococcus Candida Chlamydia Dengue E. Coli Genomics and pathogen discovery Herpesviruses Hepatitis B Hepatitis C Histoplasma HIV Human papillomavirus Immunology Leishmania Listeria Malaria Microbiota Poliovirus Pseudomonas S. aureus Streptococci Tuberculosis Viral discovery Viral transcription regulation (non-HIV) Viral vaccine development (non-HIV)

Medical Education